Observation of uterine, radial and spiral artery Doppler parameters in MIRENA applied patients due to abnormal uterin bleeding

Objective

The aim of this study was to investigate the effect of levonorgestrel secreting intrauterine device (LNG-RIA) on uterin, radial and spiral artery doppler parameters in one year follow-up.

Methods

The study included 117 fertile patients who had complaint of menometrorrhagia and who were applied LNG-RIA in Mustafa Kemal University Hospital. We observed uterine, radial and spiral artery Doppler changes during one year.

Results

Of 117 patients, 91cases comleted 1 year follow-up. While uterine artey resistivity index(RI) and pulsatility index(PI) were not changed statistically significiant, radial artery and spiral artery resistivity indices were increased. İn addition to that, endometrial thickness was decreased and levels of hemoglobine and hematocrite increased. Coogulation parameters(PT, PTT, INR) were not changed.

Conclusion 

LNG-RIA did not change significiantly uterine artery doppler parameters. İncrease in radial, spiral artery resistivity indices and decrease in endometrial thickness may be due to local progesteronic effect of LNG-RIA. No change in coogulation parameters may indicate that LNG-RIA does not change intrinsic and extrinsic coogulation pathways and doesn`t decrease vaginal bleeding via systemic effect.

Keywords

LNG-RİA, doppler of artery