The effect of anhydramnios and/or ceserian section history on duration of medical abortion

Objective

We aimed to determine that if anhydramnios and ceserian section history affect the duration of abortus in medical abortus cases with various indications and compare them with cases which have normal amnion fluid and vaginal birth history.

Methods 

This study was a retrospectively designed study. Patients who were admitted to our clinic because of medical abortion between January 2010-December 2013 were included in this study. A total of 32 pregnant women with anhydramniosis as study group and 67 pregnant women who had normal amnion fluid as control group were included in this study. Control group`s abortus indications were spina bifida, hydrocephalus, encephalocele, anencephaly, hydrops fetalis, multiple anomalies, heart anomalies(hypoplastic left heart),down syndrome, Beta thalassemia, sickle cell anemia and cystic hygroma. Patients` age, gravida, parity, gestational age, previous delivery route, duration of abortus were recorded. Misoprostol were used for medical abortion as follows: 200 mcg po and 200 mcg vaginal twice a day in patients who had prior ceserian section history and 200 mcg po and 200 mcg vaginal three times a day in patients who had prior vaginal birth history. After medical abortion, revision curettage was performed in necessary cases.

Results 

While the mean age of patients was 28,10 ± 5,72 (15-47), the mean gestational age was 17,94 ± 3,40 (10-27) weeks. 62 (%62,6) of patients had previous vaginal delivery and 28 (%28,3) of them had previous ceserian section history. 9 (%9,1) patients were primigravida. 78 (%78,8) patients had revision curettage after medical abortion. While the mean duration of abortion in anhydramnios group was 71,93 ± 47,51 h, it was 79,08 ± 52,62 h in control group. There was no statistically significiant difference between two groups according to duration of abortion(P= 0,516). While the mean duration of abortion was 69,95± 31,24 h in Patients having prior history of vaginal birth, it was 87,07± 74,38 h in patients having prior history of ceserian section. Primigravid patients had the mean duration of abortion of 91,77 ± 68,06 h. There were no statistically significiant difference in duration of abortion according to previous delivery route(p=0,220).

Conclusion 

There was no statistically significiant difference between anhydramnios group and control group according to duration of abortion. In addition to that parity and previous delivery route did not seem to affect the duration of abortus.

Keywords

Medical abortion, anhydramniosis, ceserian section history